For me it's preen in the Spring. Then hand digging the wild onion
Roundup in the walkways and patios and very carefully in the beds if needed. I have been known to 'paint' roundup mixed with a little dawn( used as a spreader sticker) onto weeds too close to prized plants. I just use a cheap dollar store foam craft brush and a baby food jar to hold my mixture. For the most part my main nemisis is wild onion and this really nasty noid weed that spreads by runners. It's in my seedling beds and everything there is done by hand. I won't risk Preen in there since I straight sow. This nasty weed crawled in from my neighbors yard
I have mostly eradicated it in the main beds and the yard.