My grandmas neighbor gave me about 15 bags of leaves that he vacuumed up but they have honey locust pods in them. Will it be ok if I rototill them one I spread the bags out or will I then be stuck with locust trees trying to come up all the time in the future? Or do I need to manually pick them out 1 by 1?

Personally... I would spread the contents on top of the beds and NOT rototill.
Re the honey locust seeds? I have experienced very poor results when I've tried to get them to grow... I wouldn't expect too many seedlings.