Its hard to know, but from what I have been told, many plants on the market now are different in various ways from plants that were around during the time period I started collecting. Every generation that gets tissue cultured apparently has the potential to change a little, because the tissue samples don't come from a single plant but from multiple plants. I don't claim to be an expert on TC at all. But I have asked a lot of questions of more knowledgeable folks. What I gleaned is that because of this method of mixing samples, that is how sometimes they get aberrant clones. Some of the these are desirable in that they are unique enough to be named as new cultivars of a plant. Some of the plants I have were not from tissue culture. They were from vegetative propagation or by seedling propagation from other collectors.
You can still get plants that are not tissue culture plants from some sources. But anything you get at a box store or nursery will likely be from TC