Hey Marcia, It really depends on the variety and the time of year if they will root easily in water. Once the nubbies appear then it's time to put them into soil. The sooner they are in soil the better the plant will be. Did you plant come with a label with a name on it? What color or name are you seeking to add?
I have been growing Brugmansias since a friend gave me one to over winter in our greenhouse in 1995. They can become addictive once you smell them at night.
Here is one of our crosses: B. kHT's Pink
B. Shorty's Variegated which was found locally.